Skin Boosters Compared: Rejuran vs Juvelook vs Skinbooster - Which One is Right for You?
If you've been researching Korean skincare treatments, you've likely encountered the term "skin booster" - a revolutionary category of injectable treatments that promise hydrated, glowing skin from within. But with multiple options like Rejuran, Juvelook, and traditional HA (Hyaluronic Acid) Skinboosters flooding the market, how do you know which one is right for your skin?
In this comprehensive guide, we'll break down the key differences between these three popular skin booster treatments, compare their ingredients, effects, prices, and help you make an informed decision based on your unique skin concerns and goals.
What Are Skin Boosters?
Skin boosters are injectable treatments designed to improve skin quality from the inside out. Unlike dermal fillers that add volume or Botox that relaxes muscles, skin boosters work at a cellular level to:
- Hydrate deeply - Deliver moisture directly into the dermal layer
- Stimulate collagen production - Improve skin elasticity and firmness
- Enhance skin texture - Reduce fine lines, pores, and acne scarring
- Restore radiance - Create a natural, healthy glow
- Regenerate skin cells - Promote healing and repair damaged tissue
The three most popular types of skin boosters in Korea are:
- Rejuran (리쥬란) - Polynucleotide-based skin healer
- Juvelook (쥬베룩) - PDLLA collagen stimulator
- HA Skinboosters - Hyaluronic acid hydration boosters
Each works through different mechanisms and addresses different skin concerns. Let's explore them in detail.
Rejuran: The Skin Regenerator
What is Rejuran?
Rejuran is a revolutionary skin booster from Korea that uses Polynucleotide (PN), a powerful ingredient derived from salmon DNA. These DNA fragments are biocompatible with human skin and work to repair damaged cells, regenerate tissue, and improve overall skin health.
How Rejuran Works
The polynucleotides in Rejuran:
- Bind to receptors in your skin cells to promote regeneration
- Improve skin elasticity by restoring the dermal matrix
- Reduce inflammation and calm irritated, sensitive skin
- Enhance moisture retention for long-lasting hydration
- Stimulate natural healing processes in damaged tissue
Best Candidates for Rejuran
Rejuran is ideal if you have:
- Dry, dehydrated skin that lacks moisture
- Sensitive or reactive skin prone to redness and irritation
- Thin, aging skin that's lost elasticity
- Dull skin tone that needs brightening
- Early signs of aging like fine lines and loss of firmness
- Acne scars or texture issues requiring repair
Rejuran Treatment Details
- Procedure time: 30-45 minutes
- Pain level: Moderate (topical numbing cream applied)
- Downtime: 1-2 days of mild redness and swelling
- Treatment interval: 3-4 sessions, 2-4 weeks apart
- Results visible: 2-4 weeks after first session
- Duration of effects: 6-12 months
- Maintenance: 1-2 sessions per year
Rejuran Pricing in Korea
- Rejuran Healer (full face): ₩400,000-650,000 ($310-$500)
- Rejuran i (eyes): ₩300,000-450,000 ($230-$350)
- Rejuran s (scars): ₩200,000-400,000 ($155-$310)
Prices as of January 2026. Exchange rate: ₩1,300 = $1 USD
Juvelook: The Collagen Stimulator
What is Juvelook?
Juvelook is a newer generation skin booster that combines PDLLA (Poly-D,L-Lactic Acid) with hyaluronic acid to deliver both immediate hydration and long-term collagen stimulation. It's often called a "liquid facelift" for its ability to improve volume and firmness.
How Juvelook Works
Juvelook's dual-action formula:
- Hyaluronic acid provides immediate hydration and plumping
- PDLLA microparticles stimulate fibroblasts to produce new collagen
- Gradually rebuilds skin structure from within
- Creates long-lasting volume and firmness
- Improves skin architecture over 3-6 months
The collagen-building process means results improve over time rather than appearing immediately.
Best Candidates for Juvelook
Juvelook works best for:
- Moderate to advanced aging signs in patients 35+
- Loss of volume and elasticity in cheeks, temples, or jawline
- Deep pores that need to be minimized
- Acne scars or atrophic scars requiring structural improvement
- Sagging skin that's lost firmness
- Combination skin concerns needing both hydration and volume
Juvelook Treatment Details
- Procedure time: 30-45 minutes
- Pain level: Low to moderate (with numbing cream)
- Downtime: Minimal - possible mild swelling for 1-3 days
- Treatment interval: 2-3 sessions, 4-6 weeks apart
- Results visible: Gradual improvement over 2-3 months
- Duration of effects: 12-24 months (Juvelook Volume up to 2 years)
- Maintenance: 1 session every 12-18 months
Juvelook Pricing in Korea
- Juvelook (full face): ₩500,000-800,000 ($385-$615)
- Juvelook Volume: ₩700,000-1,000,000 ($540-$770)
- Combination packages: ₩1,200,000-1,800,000 ($925-$1,385)
Prices as of January 2026
HA Skinboosters: The Hydration Heroes
What are HA Skinboosters?
HA (Hyaluronic Acid) Skinboosters like Restylane Vital, Profhilo, and Teosyal Redensity are pure hyaluronic acid formulations designed to flood the skin with intense hydration. They're the most straightforward type of skin booster, focusing primarily on moisture retention.
How HA Skinboosters Work
Hyaluronic acid:
- Holds up to 1,000 times its weight in water
- Attracts and binds moisture in the skin
- Creates a reservoir of hydration in the dermal layer
- Improves skin texture and smoothness
- Provides a natural plumping effect
- Enhances overall radiance and glow
Best Candidates for HA Skinboosters
HA Skinboosters are perfect if you have:
- Severely dehydrated skin from climate, age, or lifestyle
- Crepey skin texture that feels papery or thin
- No major structural concerns - just need hydration
- Younger skin (20s-30s) focusing on prevention
- Oily or combination skin that needs lightweight moisture
- Pre-event skin prep for weddings, photoshoots, etc.
HA Skinbooster Treatment Details
- Procedure time: 20-30 minutes
- Pain level: Low (very fine needles)
- Downtime: Minimal - tiny injection bumps for 12-24 hours
- Treatment interval: 2-3 sessions, 2-4 weeks apart
- Results visible: Immediate glow, full results in 1-2 weeks
- Duration of effects: 3-6 months
- Maintenance: 2-4 sessions per year
HA Skinbooster Pricing in Korea
- Restylane Vital/Vital Light: ₩300,000-500,000 ($230-$385)
- Profhilo: ₩500,000-700,000 ($385-$540)
- Teosyal Redensity I: ₩350,000-550,000 ($270-$425)
Prices as of January 2026
Side-by-Side Comparison Table
| Feature | Rejuran | Juvelook | HA Skinboosters |
|---|---|---|---|
| Main Ingredient | Polynucleotide (PN) | PDLLA + Hyaluronic Acid | Hyaluronic Acid |
| Primary Action | Cell regeneration & repair | Collagen stimulation | Deep hydration |
| Best For | Sensitive, damaged skin | Volume loss, firmness | Dehydration, glow |
| Ideal Age Range | 25-45 | 35-55 | 20-50 |
| Pain Level | Moderate | Low-Moderate | Low |
| Downtime | 1-2 days | 1-3 days | Minimal |
| Results Timeline | 2-4 weeks | 2-3 months (gradual) | Immediate |
| Effect Duration | 6-12 months | 12-24 months | 3-6 months |
| Sessions Needed | 3-4 initially | 2-3 initially | 2-3 initially |
| Price Range (USD) | $310-$500 | $385-$770 | $230-$540 |
| Maintenance | 1-2x/year | 1x/12-18 months | 2-4x/year |
| Skin Types | All, esp. sensitive | Normal to dry | All types |
Pros and Cons Breakdown
Rejuran Pros & Cons
Pros:
- ✅ Excellent for sensitive, reactive skin
- ✅ Promotes natural healing and regeneration
- ✅ Improves multiple skin concerns simultaneously
- ✅ Calms inflammation and redness
- ✅ Suitable for all skin types
- ✅ Can be combined with other treatments
Cons:
- ❌ More painful than other skin boosters
- ❌ Longer downtime (redness, swelling)
- ❌ Multiple sessions required for optimal results
- ❌ More expensive than basic HA boosters
- ❌ Not ideal if you want immediate results
Juvelook Pros & Cons
Pros:
- ✅ Longest-lasting results (12-24 months)
- ✅ Dual action: immediate + long-term benefits
- ✅ Builds structural improvement over time
- ✅ Excellent for acne scars and pores
- ✅ Less frequent maintenance needed
- ✅ Creates natural-looking volume
Cons:
- ❌ Results take time to develop (2-3 months)
- ❌ Higher upfront cost
- ❌ Not suitable for very sensitive skin
- ❌ May require careful technique to avoid lumps
- ❌ Less research than Rejuran or HA fillers
HA Skinbooster Pros & Cons
Pros:
- ✅ Immediate visible results
- ✅ Minimal downtime and discomfort
- ✅ Tried-and-true technology
- ✅ Most affordable option
- ✅ Safe for all skin types
- ✅ Quick procedure time
Cons:
- ❌ Shortest duration (3-6 months)
- ❌ Requires more frequent maintenance
- ❌ Limited structural improvement
- ❌ Primarily hydration-focused
- ❌ May not address deeper aging concerns
Which Skin Booster is Right for You?
Choose Rejuran if:
- Your skin is sensitive, thin, or easily irritated
- You have redness, rosacea, or inflammatory concerns
- You want overall skin health improvement
- You have early to moderate aging signs
- You prefer a treatment backed by extensive research
- You don't mind a few days of downtime
Choose Juvelook if:
- You're 35+ with moderate volume loss
- You want long-lasting results (1-2 years)
- You have acne scarring or enlarged pores
- You need both hydration AND structural improvement
- You're willing to wait for gradual results
- You want to minimize maintenance sessions
Choose HA Skinboosters if:
- Your main concern is dehydration and dullness
- You want immediate, visible results
- You're younger (20s-30s) focusing on prevention
- You have an upcoming event or special occasion
- You prefer minimal downtime
- You don't mind more frequent touch-ups
Can You Combine Skin Boosters?
Absolutely! In fact, combining different skin boosters is increasingly popular in Korean dermatology clinics. Common combinations include:
Rejuran + Juvelook:
- Use Rejuran first to repair skin foundation and calm inflammation
- Follow with Juvelook 2-4 weeks later to build collagen
- Ideal for comprehensive anti-aging with scar treatment
HA Skinboosters + Rejuran:
- HA provides immediate hydration and glow
- Rejuran works on deeper repair and regeneration
- Perfect for dehydrated skin needing healing
Juvelook + HA Skinboosters:
- Juvelook builds long-term structure
- HA maintains hydration between Juvelook sessions
- Great for maintaining results year-round
Always consult with a qualified dermatologist to create a customized treatment plan that addresses your specific concerns.
Recommended Clinics in Seoul
Gangnam District
1. Cheongdam Oracle Dermatology
- Specialties: Rejuran, Juvelook, combination treatments
- English Support: Yes, excellent
- Location: Near Cheongdam Station, Exit 9
- Price Range: $$$ (Premium)
- Why Choose: Expert doctors specializing in skin booster cocktails
2. April 31 Dermatology
- Specialties: All skin booster types, customized plans
- English Support: Yes
- Location: Gangnam Station, Exit 10
- Price Range: $$ (Mid-range)
- Why Choose: Comprehensive consultation, competitive pricing
3. The Face Clinic
- Specialties: Juvelook Volume, scar treatments
- English Support: Limited
- Location: Sinsa Station, Exit 8
- Price Range: $$ (Mid-range)
- Why Choose: Strong reputation for natural-looking results
Apgujeong District
4. JW Plastic Surgery Dermatology
- Specialties: Rejuran i (eyes), HA boosters
- English Support: Yes
- Location: Apgujeong Rodeo, Exit 4
- Price Range: $$$ (Premium)
- Why Choose: Luxurious facility, experienced specialists
5. Leaders Clinic
- Specialties: All skin boosters, foreigner-friendly
- English Support: Excellent
- Location: Near Apgujeong Station
- Price Range: $$ (Mid-range)
- Why Choose: Popular with international patients
Budget-Friendly Options
6. Yonsei Star Skin & Laser Clinic
- Specialties: HA Skinboosters, Rejuran
- English Support: Basic
- Location: Gangnam area (multiple branches)
- Price Range: $ (Budget-friendly)
- Why Choose: Quality care at accessible prices
Treatment Tips and What to Expect
Before Your Treatment
- Avoid blood thinners (aspirin, ibuprofen) for 3-5 days
- Skip retinol and acids for 2-3 days before
- Stay hydrated - drink plenty of water
- Avoid alcohol 24 hours before
- Arrive with clean skin - no makeup
- Bring photos of your skin concerns to show the doctor
During Your Treatment
- Numbing cream applied for 15-20 minutes
- Multiple small injections across treatment area
- Gentle massage to distribute product evenly
- Total procedure time: 20-45 minutes
- Mild stinging or pressure sensation
After Your Treatment
Immediate (First 24 hours):
- Mild redness and swelling (normal)
- Small injection bumps (will resolve)
- Avoid makeup for 6-12 hours
- Apply ice packs if needed
- No exercise or sauna
First Week:
- Swelling subsides by day 2-3
- Avoid sun exposure and use SPF 50+
- No harsh skincare or exfoliation
- Sleep on your back
- Avoid alcohol and smoking
Long-term Care:
- Maintain regular skincare routine
- Use gentle, hydrating products
- Protect skin from sun damage
- Stay hydrated internally
- Follow doctor's recommendations for touch-ups
Frequently Asked Questions
Q: Are skin boosters painful? A: Most clinics apply numbing cream 15-20 minutes before treatment. Rejuran tends to be slightly more uncomfortable than HA boosters or Juvelook. Pain is typically described as mild stinging or pressure.
Q: How long do results last? A: HA Skinboosters last 3-6 months, Rejuran lasts 6-12 months, and Juvelook provides the longest results at 12-24 months. Individual results vary based on age, lifestyle, and skin condition.
Q: Can I combine skin boosters with Botox or fillers? A: Yes! Many patients combine treatments for comprehensive facial rejuvenation. Typically, skin boosters are done first, followed by Botox or fillers 1-2 weeks later, or vice versa depending on your doctor's recommendation.
Q: What's the difference between skin boosters and dermal fillers? A: Dermal fillers add volume to specific areas (lips, cheeks, nasolabial folds) while skin boosters improve overall skin quality, hydration, and texture throughout the entire treatment area without adding significant volume.
Q: Are there any side effects? A: Common side effects include temporary redness, swelling, bruising, and small bumps at injection sites. Serious complications are rare when performed by qualified professionals. Always choose licensed dermatologists.
Q: How much does a full course of treatment cost? A: Budget $800-$1,500 for a complete initial treatment course (2-4 sessions) depending on which skin booster you choose. Maintenance costs $300-$800 per session.
Q: Can men get skin booster treatments? A: Absolutely! Skin boosters are increasingly popular among men seeking to improve skin texture, reduce pores, and maintain a youthful appearance without obvious cosmetic changes.
Q: When will I see results? A: HA Skinboosters show immediate hydration glow. Rejuran results appear in 2-4 weeks. Juvelook takes the longest, with gradual improvement over 2-3 months as collagen builds.
Final Recommendations
Choosing between Rejuran, Juvelook, and HA Skinboosters ultimately depends on your specific skin concerns, budget, and desired timeline for results:
Best Overall Value: Juvelook offers the longest-lasting results, making it the most cost-effective option over time despite higher upfront costs.
Best for Sensitive Skin: Rejuran's healing and regenerative properties make it the top choice for reactive, damaged, or thin skin.
Best for Immediate Results: HA Skinboosters deliver instant hydration and glow, perfect for special events or quick skin refreshes.
Best for Prevention: Young patients in their 20s-30s benefit most from HA Skinboosters or Rejuran to maintain skin quality before major aging signs appear.
Best for Anti-Aging: Patients 35+ with moderate aging should consider Juvelook or a combination of Rejuran + Juvelook for comprehensive rejuvenation.
Don't hesitate to book consultations at multiple clinics to compare recommendations. Reputable Korean dermatologists will provide honest assessments and create customized treatment plans based on your unique needs rather than pushing the most expensive option.
Ready to transform your skin from within? Seoul's advanced dermatology clinics offer some of the world's most innovative skin booster treatments at competitive prices. Book your consultation today and discover which skin booster is perfect for your skin journey!
⚠️ Medical Disclaimer: This article provides general information about skin booster treatments including Rejuran, Juvelook, and HA Skinboosters. It is not intended as medical advice and should not replace professional consultation. Always consult with a qualified, licensed dermatologist or healthcare professional before undergoing any cosmetic procedure. Individual results may vary, and all treatments carry potential risks and side effects. Ensure your chosen clinic and practitioner are properly licensed and experienced in administering these treatments.
Last Updated: January 5, 2026 Reading Time: 12 minutes
